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Table 1 Strategies to increase the pharmaceutical supply chain resilience to sanctions

From: Strategies to improve pharmaceutical supply chain resilience under politico-economic sanctions: the case of Iran

Main themes

Subthemes

Final codes

Health policy and management

Revisions in Iran’s health management

Ban the importation of drugs that can be produced domestically

Elimination of the pharmaceutical mafia in the Ministry of Health

Consideration of health economics

Planning for funding and transportation of funds

Improving the resilience of the pharmaceutical system and preparing appropriate plans

More attention to the efficiency of the system

Reducing the authorization to establish pharmacies and clinics to prevent induced demand

Increasing and strengthening oversight

Incorporating information and monitoring systems into a health problem

Increasing the efficiency of control instruments for pharmacies and clinics

Harmonization of control instruments in medical universities

Rapid detection of corruption and precise and targeted fight against it

Prevention of prescriptions against the pharmacopeia

Control with the aim of improvement and not punishment

Provision of clinical guidelines

Considering clinical guidelines as a lost chain in Iran

Considering clinical guidelines as a tool for treatment management

Customizing consideration of clinical guidelines according to local needs

Delegation and privatization

Delegation to medical universities by the Ministry of Health

Strengthening the authority of the private sector and pharmacists

Decentralization

Outsourcing of hospital pharmacies

Privatization of services

Centralized and strategic purchasing

Use of centralized and pooled procurement to get great deals

Need for information transparency with pooled and centralized purchasing

Separation of purchaser and observer

Private or semi-public holdings

Separation of pharmaceutical accounts from other accounts

Separate payment for different entities

Proper implementation of the GP plan and referral system

Existing government for patient health management

Correction of the primary care physician and referral system

Prevention of patient perplexity in choosing doctor and medications

Existing systematic relationship between the referral system and the food and drug authority

Utilization of potentials and infrastructure in Iran

Strengthening of inter-sectoral cooperation

National tender for the production of medical devices

Use of military facilities to manufacture medical devices

Creation of relationships between the medical industry, the Department of Defense, the electronics industry, and universities

Allocating contracts to universities to manufacture pharmaceuticals according to their potentials

More attention to mass media

The crucial role of the media in improving the situation under sanctions and bringing peace to the society

The positive role of the media in society justification and decreasing crises

Improving public relations in medical universities in the field of pharmaceuticals

Creating a free space for information flow and preventing political favoritism

The crucial role of the media in increasing politicians’ accountability

Accurate news reporting to increase public confidence

Use of competent advisors to health managers in the media field

Relying on national and religious power and authority

Improving religious and patriotic passions and enthusiasm

Improvement of sympathy and empathy in society

Use of social and human capital

Improving people's self-assessment

Relations with other countries

Interactions with neighboring countries

Planning to take advantage of neighbors

Increasing cooperation with Islamic countries and the Middle East

Increasing cooperation with Islamic countries and the Middle East

Formation of joint funds between Islamic countries for pharmaceuticals

Management and development of health tourism

Determining the management of health tourism

Reducing the power of brokers in the field of health tourism

Receiving patients' bills in the form of international currencies

Reducing the problems related to visas for health tourism

Bringing needed medicines and medical devices by health tourists

Sale of equipment at its real price (without additional costs) to health tourists

Pricing processes

Increasing expenditure on domestic medicine

Increase in the price of medicines and medical equipment together with the increase in the currency

Addressing price instability

Increase in the price of cheap medicines

Continuation of the plan of branded generics and increase in the price of domestic products up to 50% of the cost of their branded counterparts

Rationalization of the prices of medicines

Reducing import and increasing production through rational pricing of medicines

Consideration of transportation costs in pricing

Elimination of counterfeiting through real pricing

Change in the pharmaceutical price according to the value of major international currencies

Management of insurance organizations

Strengthening the insurance system

Payment of the pharmaceutical subsidies to insurance organizations

Insurance coverage to cover pharmaceutical price increase

Complimentary insurance role for those in higher percentiles

Crossover subsidiary

Mandatory insurance for all people

Removal of unnecessary medications from the list of insurance benefits

Removal of luxury and cosmetic drugs from basic coverage

Increasing coverage for generic and low-cost brands

Elimination of brands for which generic alternatives exist

Revising the basic benefits package

Revising the basic benefits package

Transforming insurance into an industry

Research by insurance organizations on ways to reduce drug costs

Cost-effectiveness research on pharmaceuticals

Control of insurance companies over the way medicines are consumed

Pricing and monitoring the funds

Changes in insurance methods

Integrated health information system

Electronic health record

Integration of health information systems

Use of the health care system to reduce the financial burden

Definition of services and drugs in the integrated system

Preparing facilities for the introduction of the smart health card

Electronic prescription

Electronic prescribing to reduce treatment burden

Electronic facilities in rural areas for the development of electronic prescribing

Electronic prescribing as a tool to control prescribing

Defining a system to select the best drugs according to the cost and symptoms of a disease

Mechanization of the distribution system

Medication tracking

Tracking of medicines from distribution to consumption

Online relationship between MOH and distributors and importers

Design of a mechanized system for prescribing

Channelized distribution through a digital system

Control and monitoring of pharmacies and distributors

Prevention of hoarding of medicines in pharmacies

Prevention of the over-the-counter sale of medicines in pharmacies

Reduction in the number of brokers in the distribution system

Reduction in the number of distributors

Correct planning for daily exclusion of medicines from distribution companies

Role of suppliers and manufacturers

Provision of high-quality medicines

Increasing the quality of domestic drugs and medical devices

More attention to the quality of domestic supplements

In vivo and in vitro evaluation of drugs by the government

Evaluation of the source substance of medicines by the MOH

Improving the quality of domestic production through interaction between manufacturers, prescribers, and consumers

Increasing the warranty of domestic products

Increasing production and exports

More planning to increase domestic products

Production of medicines and medical devices for domestic use and export

Attention to the export of high-tech drugs and generics

Financing the provision of the initial substance through the development of drug export

Profitability through large-scale drug production

Role of the medical community and consumers

Informing the medical community

Increasing the knowledge of the medical community about domestic products

Increasing physicians’ and pharmacists’ knowledge about the costs and combinations of medicines

Strengthening the relation between pharmacies and the physicians

Physician access to the software containing drug lists, costs, and indication for prescribing

Raising physician awareness of the national pharmacopeia

Developing a culture of rational use of medicines and prohibiting self-medication

Emphasizing traditional Iranian medicine

Prohibition of prescribing non-indicated and expensive medicines

Use of alternative medicines and methods

Use of simple and effective pharmaceutical protocols

Not using the most sophisticated methods for all cases

Justification and encouragement of patients to use alternative medicines

Substitution of monopolistic drugs by others

Determining the alternatives of 1,2,3 of treatment

Attention to the treatment priorities and collaborative decision making

Role of providers regarding lack of brand loyalty

Less attention to international brands

Greater oversight over the prescription of branded drugs

Prescribers’ lack of vested interest in recommending a certain manufacturer’s products

Improving medical ethics to limit branding

Providers’ and prescribers’ positive attitude towards domestic drugs

Consumer–patient collaboration

Rational prescribing of medications

Improving patients' culture and knowledge about medication use

Encouraging patients to use domestic medicines