Table 4 OintmentY cluster themes identified by HDBSCAN algorithm
From: Advancing medical affair capabilities and insight generation through machine learning techniques
OintmentY cluster themes | ||
|---|---|---|
Cluster | Themes | Potential explorations |
Cluster -1 | Not enough cases to be identified as a cluster: Price is too expensive | N/A |
Cluster 0 | Question missing | N/A |
Cluster 1 | Question missing | N/A |
Cluster 2 | Market research- Off label use not caused by atopic dermatitis | N/A |
Cluster 3 | Question missing | N/A |
Cluster 4 | Requests for slide decks | Data visualization: MUFASA |
Cluster 5 | Does OintmentY contain "…" (Ingredients) | Med Info Website |
Cluster 6 | Request for dosing information in children < 2 years old | Med Info Website |
Cluster 7 | Facial flush use with alcohol | Med Info Website, Educate pharmacists (part of counselling) |
Cluster 8 | Availability of OintmentY | Date visualization: MUFASA (Compare it with inquiry of stability once opened questions) |
Cluster 9 | Off label use with vitiligo | Data visualization: MUFASA |
Cluster 10 | Is there a Compassionate Use Program (CUP)? | Med Info Website (Instructions, Forms) |
Cluster 11 | CUP process | |
Cluster 12 | Off label use in sensitive area (eyes, face, gluteal cleft) | Data visualization: MUFASA |
Cluster 13 | Maximum dose/maximum duration to use | Med Info Website |
Cluster 14 | PV-AE types of report | Data visualization: MUFASA |
Cluster 15 | PV-AE Types of report with PSP# provided | Data visualization: MUFASA |
Cluster 16 | Patient experiencing AE and wanting reimbursement | Data visualization: MUFASA |
Cluster 17 | OintmentY use off label- inside mouths | Data visualization: MUFASA |
Cluster 18 | Can it be used in sensitive reproductive areas? (genitals) | Med Info Website |
Cluster 19 | Requests for OintmentY/DrugC Study | Med Info Website #Inquiry vs time to see if # of questions change following a) rep handling of long-term safety/cancer warning message with Trial data b) removal of boxed warning |
Cluster 20 | Request for Off label use data for Vitiligo | Data visualization: MUFASA |
Cluster 21 | Request for information for off-label uses in other types of areas | Data visualization: MUFASA |
Cluster 22 | The use of OintmentY with/without steroids + Why is OintmentY second line? | Med Info Website |
Cluster 23 | Phototherapy/sunlight | Med Info Website, educate pharmacists (part of counselling) |
Cluster 24 | Use on eyelids/getting into the eyes | Med Info Website, educate pharmacists (part of counselling) |
Cluster 25 | Malignancy/cancer risks | Med Info Website Changes in inquiry frequency over time to see if PM change (removal of boxed warning) has had an impact |
Cluster 26 | Safety concerns: renal failure | Med Info Website |
Cluster 27 | Product defect: difficulty getting ointment out of tube | Product feedback |
Cluster 28 | Request on information for the use on children under the age of 2 | Med Info Website |
Cluster 29 | Request on information for the use on children under the age of 2 (provides strength in questions) | Med Info Website |
Cluster 30 | In-use stability of tube once opened | Data visualization: MUFASA (Has it been increasing?) |
Cluster 31 | Doctor recommends putting tube in fridge | Opportunities to educate doctors/pharmacists to know that the stability is compromised once put in fridge Med Info Website should upload information about refrigeration and stability |