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Table 6 Bivariable and multivariable logistic regression analyses

From: Potentially inappropriate medicine use and predicting risk factors in hospitalized older adult patients: findings of a prospective observational study from Ethiopia

Variables

PIM (Yes)

PIM (No)

Bivariable analysis

Multivariable analysis

COR (95%CI)

p value

AOR (95%CI)

p value

Sex

 Male

93 (78.81)

41 (93.18)

1

 

1

 

 Female

25 (21.19)

3 (6.82)

3.67 (1.05, 12.86)

0.042

2.69 (0.49, 14.92)

0.255

Khat chewing

   

0.155

  

 Never

35 (29.66)

10 (22.73)

1

 

1

 

 Former

77 (65.25)

28 (63.64)

0.79 (0.34, 1.79)

0.567

0.60 (0.19, 1.9)

0.388

 Current

6 (5.08)

6 (13.64)

0.29 (0.07, 1.08)

0.065

0.25 (0.04, 1.74)

0.162

Activities of daily living

   

0.105

  

 Dependent

42 (35.59)

23 (52.27)

0.38 (0.15, 0.96)

0.041

0.59 (0.16, 2.23)

0.441

 Partially dependent

38 (32.20)

13 (29.55)

0.62 (0.23, 1.65)

0.336

0.51 (0.14, 1.86)

0.305

 Fully independent

38 (32.20)

8 (18.18)

1

 

1

 

Acute kidney injury

 Yes

21 (17.80)

4 (9.09)

2.16 (0.69, 6.71)

0.181

1.59 (0.38, 6.66)

0.528

 No

97 (82.20)

40 (90.91)

1

 

1

 

Asthma

 Yes

5 (4.24)

4 (9.09)

0.44 (0.11, 1.73)

0.241

0.12 (0.01, 0.17)

0.068

 No

113 (95.76)

40 (90.91)

1

 

1

 

Community acquired pneumonia

 Yes

50 (42.37)

11 (25)

2.21 (1.02, 4.78)

0.045

0.77 (0.26, 2.23)

0.625

 No

68 (57.63)

33 (75)

1

 

1

 

Heart failure

 Yes

55 (46.61)

2 (4.55)

18.33 (4.24, 79.25)

0.000

7.35 (1.25, 43.2)

0.027

 No

63 (53.39)

42 (95.45)

1

 

1

 

Hemiplegia

 Yes

6 (5.08)

5 (11.36)

0.42 (0.12, 1.45)

0.168

3.66 (0.39, 34.43)

0.256

 No

112 (94.92)

39 (88.64)

1

 

1

 

Systemic hypertension

 Yes

42 (35.59)

19 (43.18)

0.73 (0.36, 1.47)

0.376

0.64 (0.18, 2.27)

0.490

 No

76 (64.41)

25 (56.82)

1

 

1

 

Stroke

 Yes

7 (5.93)

12 (27.27)

0.17 (0.06, 0.46)

0.001

0.17 (0.02, 1.57)

0.119

 No

111 (94.07)

32 (72.73)

1

 

1

 

Pulmonary hypertension

 Yes

10 (8.47)

1 (2.27)

3.98 (0.49, 32.05)

0.194

1.07 (0.09, 13.43)

0.956

 No

108 (91.53)

43 (97.73)

1

 

1

 

Thrombocytopenia

 Yes

4 (3.39)

6 (13.64)

0.22 (0.06, 0.83)

0.025

0.17 (0.03, 1.88)

0.035

 No

114 (96.61)

38 (86.36)

1

 

1

 

Cardiomyopathy

 Yes

33 (27.97)

2 (4.55)

8.15 (1.87, 35.61)

0.005

2.55 (0.34, 18.9)

0.360

 No

85 (72.03)

42 (95.45)

1

 

1

 

Number of diseases, median (IQ)

4 (3, 5)

3 (2, 4)

1.52 (1.16, 1.99)

0.002

1.28 (0.89, 1.84)

0.188

 1

5 (4.2)

3 (6.8)

1

   

 2

15 (12.7)

15 (34.1)

0.6 (0.12, 2.97)

0.532

0.92 (0.13, 6.65)

0.937

 3

34 (28.8)

12 (27.3)

1.7 (0.35, 8.21)

0.509

2.58 (0.35, 18.97)

0.351

 4

29 (24.6)

10 (22.7)

1.74 (0.35, 8.63)

0.498

1.47 (0.2, 10.8)

0.705

 ≥ 5

35 (29.7)

4 (9.1)

5.25 (0.9, 30.7)

0.066

4.99 (0.49, 51.27)

0.176

Number of in hospital medications

 1–4

22 (18.6)

21 (47.7)

1

0.000

  

 5–9

81 (68.6)

22 (50)

3.51 (1.64, 7.52)

0.001

2.25 (0.84, 6.01)

0.107

 ≥ 10

15 (12.7)

1 (2.3)

14.32 (1.73, 118.18)

0.013

10.75 (0.99, 116.2)

0.051

  1. AOR adjusted odd ratio, COR crude odd ratio, PIM potentially inappropriate medication