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Table 2 Likelihood of receiving testing

From: Pharmacogenetic testing and monitoring of complete blood counts among Veterans newly prescribed thiopurine treatments: a retrospective cohort study

 

Tested by CBC or PGx

PGx testing only

 

O.R. (95% CI)

p value

O.R. (95% CI)

p value

Drug type

    

 Azathioprine

Ref.

 

Ref.

 

 Mercaptopurine

0.84 (0.80–0.88)

 < 0.05

0.95 (0.90–0.99)

 < 0.05

 Thioguanine

0.56 (0.41–0.76)

 < 0.05

0.39 (0.26–0.59)

 < 0.05

Prescribing Dx or stop code

    

 Dermatology

Ref.

 

Ref.

 

 Gastroenterology

1.13 (1.02–1.26)

0.25

0.91 (0.83–0.99)

0.26

 Hematology

0.71 (0.55–0.91)

 < 0.05

0.05 (0.04–0.07)

 < 0.05

 Oncology

0.65 (0.52–0.82)

0.07

0.05 (0.04–0.07)

 < 0.05

 Rheumatology

0.19 (0.17–0.21)

 < 0.05

0.12 (0.11–0.13)

 < 0.05

 Transplant

0.76 (0.69–0.85)

0.01

0.55 (0.51–0.61)

 < 0.04

 Other

0.60 (0.39–0.91)

0.23

0.07 (0.04–0.13)

 < 0.05

Age

0.99 (0.99–0.99)

 < 0.05

0.99 (0.99–0.99)

 < 0.05

Sex

    

 Male

Ref.

 

Ref.

 

 Female

0.95 (0.90–1.00)

0.28

1.00 (0.95–1.04)

0.92

Racea

    

 White

Ref.

 

Ref.

 

 Black or African American

1.30 (1.24–1.36)

 < 0.05

1.24 (1.19–1.30)

 < 0.05

 Asian

1.74 (1.42–2.14)

 < 0.06

1.41 (1.18–1.69)

 < 0.05

 Native Hawaiian or Other Pacific Islander

0.77 (0.65–0.91)

0.13

0.89 (0.75–1.06)

0.50

 American Indian or Alaska Native

1.16 (0.95–1.40)

0.45

1.09 (0.90–1.32)

0.65

 Unknown

0.97 (0.91–1.04)

0.70

1.00 (0.93–1.07)

1.00

Ethnicitya

    

 Not Hispanic or Latino

Ref.

 

Ref.

 

 Hispanic or Latino

1.16 (1.08–1.25)

 < 0.05

1.08 (1.01–1.16)

0.27

 Unknown

0.69 (0.63–0.76)

 < 0.05

0.84 (0.76–0.93)

 < 0.05

  1. aRace and ethnicity information about patients was self-reported and taken from the EHR