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Table 4 Healthcare professionals` knowledge of potential drug–drug interactions in general hospitals of Buraydah

From: Knowledge and information sources of potential drug–drug interactions of healthcare professionals among Buraydah Hospitals

Drug pairs

Contra-indicated

N [%]

Could be used under monitoring

N [%]

No interaction

N [%]

Not sure

N [%]

Acetaminophen with codeine + amoxicillin

6 [4.4]

5 [3.7]

90 [66.7]*

34 [25.2]

Carbamazepine + clarithromycin

26 [19.3]

42 [31.1]*

16 [11.9]

51 [37.8]

Digoxin + verapamil

24 [17.8]

52 [38.5]*

10 [7.4]

49 [36.3]

Digoxin + clarithromycin

13 [9.6]

43 [31.9]*

22 [16.3]

57 [42.2]

Digoxin + sildenafil

13 [9.6]

24 [17.8]

40 [29.6]*

58 [43.0]

Metformin + erythromycin

2 [1.5]

13 [9.6]

58 [43.0]*

62 [45.9]

Nitroglycerin + sildenafil

75 [55.6]*

15 [11.1]

5 [3.7]

40 [29.6]

Simvastatin + itraconazole

33 [24.4]*

26 [19.3]

15 [11.1]

61 [45.2]

Warfarin + cimetidine

26 [19.3]

38 [28.1]*

18 [13.3]

53 [39.3]

Atenolol + ranitidine

1 [0.7]

12 [8.9]

58 [43.0]*

64 [47.4]

Carbamazepine + cimetidine

14 [10.4]

38 [28.1]*

22 [16.3]

61 [45.2]

Warfarin + fluconazole

47 [34.8]*

24 [17.8]

11 [8.1]

53 [39.3]

Allopurinol + pyrazinamide

15 [11.1]*

12 [8.9]

32 [23.7]

76 [56.3]

Praziquantel + rifampicin

34 [25.2]*

15 [11.1]

10 [7.4]

76 [56.3]

Warfarin + co-trimoxazole

35 [25.9]*

20 [14.8]

16 [11.9]

64 [47.4]

  1. *Correct responses