Table 2 Responses of pharmacists on knowledge-related questions of RDQ-13 scale
| Â | Yes | % | No | % |
|---|---|---|---|---|
Domain 1: Related to renal dose adjustment | ||||
 a. Are you knowledgeable about renal dose adjustment? | 241 | 89.3 | 29 | 10.7 |
 b. Have you ever heard about the National Kidney Foundation KDOQI guidelines? | 129 | 47.8 | 141 | 52.2 |
 c. Are the medications excreted from the body through the kidneys? | 267 | 98.9 | 3 | 1.1 |
 d. Are you monitoring a patient's renal function during medication administration? | 202 | 74.8 | 68 | 25.2 |
Domain 1: Overall score (mean ± SD) | 3.11 ± 0.88 | |||
Domain 2: Factors to be considered when determining the appropriate dose for a patient with renal impairment | ||||
 Age of the patient | 258 | 95.6 | 12 | 4.4 |
 Weight of the patient | 258 | 95.6 | 12 | 4.4 |
 The severity of the patient's renal impairment | 263 | 97.4 | 7 | 2.6 |
 The medication's pharmacokinetics and pharmacodynamics | 256 | 94.8 | 14 | 5.2 |
Domain 2: Overall score (mean ± SD) | 3.83 ± 0.45 | |||
Domain 3: Medications commonly require renal dose adjustment | ||||
 Antibiotics | 252 | 93.3 | 18 | 6.7 |
 Antihypertensive | 213 | 78.9 | 57 | 21.1 |
 Analgesics | 195 | 72.2 | 75 | 27.8 |
 Other medications | 236 | 87.4 | 34 | 12.6 |
Domain 3: Overall score (mean ± SD) | 3.32 ± 0.84 | |||
Domain 4: Calculating the appropriate dose for a patient with renal impairment | ||||
 Use a formula based on the patient's creatinine clearance or estimated glomerular filtration rate (eGFR) | 261 | 96.7 | 9 | 3.3 |
 Follow dosing guidelines provided by the medication manufacturer | 225 | 83.3 | 45 | 16.7 |
 Consult with a specialist, such nephrologist | 239 | 88.5 | 31 | 11.5 |
 Consult with a specialist, such as a pharmacist | 261 | 96.7 | 9 | 3.3 |
Domain 4: Overall score (mean ± SD) | 3.65 ± 0.61 | |||
Domain 5: Consequences of not adjusting the dose of medications for patients with renal impairment | ||||
 Increased risk of adverse drug reactions | 259 | 95.9 | 11 | 4.1 |
 Decreased medication efficacy | 202 | 74.8 | 68 | 25.2 |
 Reduced quality of life for the patient | 256 | 94.8 | 14 | 5.2 |
 Exaggerate symptoms of disease | 243 | 90.0 | 27 | 10.0 |
Domain 5: Overall score (mean ± SD) | 3.56 ± 0.79 | |||
Domain 6: Resources to determine the appropriate dose for a patient with renal impairment | ||||
 Medication dosing guidelines | 261 | 96.7 | 9 | 3.3 |
 Clinical practice guidelines | 259 | 95.9 | 11 | 4.1 |
 Pharmacokinetic information | 261 | 96.7 | 9 | 3.3 |
 Pharmacodynamics information | 237 | 87.8 | 33 | 12.2 |
Domain 6: Overall score (mean ± SD) | 3.77 ± 0.53 | |||
Overall Knowledge score (mean ± SD) | 21.24 ± 2.18 | |||