Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis

Kebede, Bekalu; Getachew, Melese; Agegnew, Samuel; Dagnew, Ephrem Mebratu; Abebe, Dehnnet; Belayneh, Anteneh; Tegegne, Bantayehu Addis; Kebede, Tiringo; Kiflu, Mekides; Biyazin, Yalemgeta; Alamneh, Yoseph Merkeb

doi:10.1186/s40545-023-00603-7

Journal of Pharmaceutical Policy and Practice

Table 3 Subgroup analysis of articles describing medications used based on types of ACS

From: Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis

Type of ACS	Management	Total sample size	Frequency of medication used	Pooled prevalence (95%CI)	References
STEMI	Aspirin	1069	522	56.903 (38.032–75.774)	[21,22,23, 25, 28]
	Clopidogrel	1069	502	55.266 (35.946–74.586)	[21,22,23, 25, 28]
	Heparin	1069	446	47.273 (34.865–59.680)	[21,22,23, 25, 28]
	BB	598	307	51.591 (41.320–61.862)	[21, 22, 25, 28]
	ACEIs/ARBs	1069	450	43.441 (35.609–51.272)	[21,22,23, 25, 28]
	Nitrates	589	135	22.823 (14.240–31.406)	[21, 22, 25, 28]
	Statins	1069	473	51.803 (33.990–69.617)	[21,22,23, 25, 28]
	CCBs	888	85	7.782 (− 0.473–16.038)	[21,22,23, 28]
	Anti-pains	1069	276	25.505 (17.549–33.460)	[21,22,23, 25, 28]
	PCI	456	206	24.558 (3.495–45.621)	[21, 22, 25]
NSTEMI	Aspirins	1069	266	23.130 (15.545–30.714)	[21,22,23, 25, 28]
	Clopidogrel	1069	244	21.098 (14.001–28.195)	[21,22,23, 25, 28]
	Heparin	1069	231	19.891 (14.158–25.624)	[21,22,23, 25, 28]
	BB	598	181	18.734 (10.020–27.448)	[21, 22, 25, 28]
	ACEIs/ARBs	1069	198	16.963 (10.290–23.635)	[21,22,23, 25, 28]
	Nitrates	589	47	9.890 (4.206–15.574)	[21, 22, 25, 28]
	Statins	1069	262	21.779 (14.446–29.113)	[21,22,23, 25, 28]
	Anti-pains	1069	171	12.009 (3.179–20.840)	[21,22,23, 25, 28]
UA	Aspirin	888	249	22.703 (8.816–36.590)	[21,22,23, 28]
	Clopidogrel	888	214	20.666 (5.646–35.686)	[21,22,23, 28]
	Heparin	888	202	16.282 (1.754–30.809)	[21,22,23, 28]
	BB	417	66	14.331 (5.416–23.246)	[21, 22, 28]
	ACEIs/ARBs	888	197	15.365 (2.619–28.112)	[21,22,23, 28]
	Nitrates	417	28	5.960 (0.359–11.561)	[21, 22, 28]
	Statins	888	214	19.897 (7.262–32.532)	[21,22,23, 28]
	CCBs	888	81	6.302 (− 1.493–14.097)	[21,22,23, 28]
	Anti-pains	764	174	17.908 (2.402–33.414	[21, 23, 28]

ACS acute coronary syndrome, ACEIs/ARBs angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, BBs beta-blockers, CCBs calcium channel blockers, CI confident interval, PCI percutaneous coronary intervention, STEMI non-ST-elevation myocardial, NSTEMI ST-elevation myocardial infarction, UA unstable angina

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ISSN: 2052-3211

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