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Table 3 Clinical outcomes at day-seven and day-thirty

From: Clinical impact of multidisciplinary carbapenem stewardship interventions: a retrospective cohort study

Outcomes

Total

n (%)

Accepted

n (%)

Not-accepted

n (%)

p-value

Outcomes at day-7

    

TWBC trend

   

0.578a

 Decreasing or normalised

114 (81.4)

85 (74.6)

29 (25.4)

 Increasing or elevated

26 (18.6)

18 (69.2)

8 (30.8)

CRP trendd

   

0.533b

 Decreasing or normalised

52 (75.3)

39 (75.0)

13 (25.4)

 Increasing or elevated

17 (24.6)

11 (64.7)

6 (35.3)

Temperature

   

0.164a

 Afebrile

113 (80.7)

86 (76.1)

27 (23.9)

 Febrile

27 (19.3)

17 (63.0)

10 (37.0)

Outcome at day-30

    

 Discharged well

72 (51.4)

55 (76.4)

17 (23.6)

0.568b

 Mortality

46 (32.9)

33 (71.7)

13 (28.3)

 Still hospitalised (ill)

12 (8.6)

7 (58.3)

5 (41.7)

 Still hospitalised (improving)

10 (7.1)

8 (80.0)

2 (20.0)

Length of stay (days)

   

0.526c

 Median

(IQR)

34.5

(30.5–48.5)

36.0

(23.5–48.5)

30.0

(11.5–48.5)

  1. Normalising or decreasing trend: TWBC approaching 4.0-11.0 x 109/L or CRP approaching <10.0mg/L
  2. Increasing or elevated trends: TWBC increasing above 11.0 × 109/L and CRP >10mg/L.
  3. Febrile: temperature >37 °C, afebrile: temperature =37 °C
  4. aChi-square test. bFisher’s exact test. cMann Whitney test
  5. dN = 69 as repeated CRP levels were not available for the remaining 71 cases