Table 2 Types of carbapenem drug-related problems identified, its causes and interventions made

Drug-related problems (DRP)

0.784^b

 Unnecessary antibiotic treatment

137 (97.9)

101 (73.7)

36 (26.3)

 No effect or therapy failure

3 (2.1)

2 (66.7)

1 (33.3)

Causes of DRP

0.802^a

 No indication for carbapenem use

77 (55.0)

56 (72.7)

21 (27.3)

 Inappropriate antibiotic choice according to the guideline

63 (45.0)

47 (74.6)

16 (25.4)

Types of interventions

0.136^b

 Discontinuation

70 (50.0)

47 (67.1)

23 (32.9)

 De-escalation

67 (47.9)

54 (80.6)

13 (19.4)

 Escalation

3 (2.1)

2 (66.7)

1 (33.3)