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Table 3 Interrupted time series analysis results for utilization of antibiotics under price control, by sub-therapeutic categories

From: Evaluating the impact of price regulation (Drug Price Control Order 2013) on antibiotic sales in India: a quasi-experimental analysis, 2008–2018

Subtherapeutic categories

Time (p value)

Intervention (p value)

Time after intervention (p value)

Constant (p value)

Goodness of fit (R2)

Aminoglycosides

− 0.001 (0.41)

− 0.170 (0.08)

0.002 (0.42)

14.45 (0.00)

0.94

Broad spectrum penicillin

0.009 (0.00)

0.238 (0.00)

− 0.002 (0.35)

17.43 (0.00)

0.98

Narrow spectrum penicillin

0.002 (0.93)

0.355 (0.44)

0.021 (0.68)

12.08 (0.00)

0.40

Cephalosporins

0.006 (0.00)

− 0.011 (0.88)

− 0.006 (0.56)

17.98 (0.00)

0.98

Fluroquinolones

− 0.001 (0.39)

− 0.065 (0.43)

0.002 (0.50)

18.19 (0.00)

0.97

Macrolides

0.005 (0.00)

0.180 (0.02)

− 0.007 (0.01)

17.30 (0.00)

0.98

Tetracyclines

− 0.014 (0.00)

− 2.11 (0.00)

− 0.004 (0.28)

18.83 (0.00)

0.97

Trimethoprim and combinations

0.002 (0.73)

0.291 (0.10)

− 0.024 (0.00)

17.66 (0.00)

0.90

Other antibacterials

0.006 (0.00)

0.878 (0.00)

− 0.010 (0.00)

10.56 (0.00)

0.88