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Table 4 Cox regression analysis of predictors of mortality among children on ART at East Gojjam zone public hospitals, Amhara regional state, North West Ethiopia, 2019 (N = 251)

From: Survival and predictors of mortality among HIV-positive children on antiretroviral therapy in public hospitals

Variables

Death N (%)

Censored N (%)

CHR (95% CI)

AHR (95% CI)

p-value

Age

  < 1 year

4 (25)

15 (6.4)

10.57(2.94, 8.02)

8.92(2.62,30.36)

0.000

 1–5 year

6 (37.5)

47 (20.0)

4.54 (1.46, 14.16)

6.42(1.4, 29.5)

0.017

   ≥ 5 year

6 (37.5)

173 (73.6)

1

1

 

CD4 count

 Below threshold

12 (75)

52 (23.0)

9.27 (2.98, 28.76)

3.55(1.08, 11.67)

0.037

 Above threshold

4 (25)

174 (77.0)

1

1

 

Hemoglobin

  < 10 mg/dl

11 68.8)

40(17.2)

9.26(2.98, 28.76)

5.04(1.54, 16.55)

0.008

   ≥ 10 mg/dl

5 (31.2)

193 (82.8)

1

1

 

Baseline WHO stage

 Stage I &II

6 (37.5)

149 (63.4)

0.36(0.13, − 0.99)

0.45(0.16, 1.28)

0.113

 Stage III & IV

10 (62.5)

86 (36.6)

1

1

 

Taking CPT

 Yes

5 (31.3)

178 (75.7)

1

1

 

 No

11 (68.8)

57 (24.3)

4.95 (1.71, 14.30)

2.5(1.16, 8.20)

0.034

Opportunistic infections

 Yes

10 (62.5)

65 (27.7)

3.78 (1.37, 10.38)

2.18(0.63, 7.57)

0.222

 No

6 (37.5)

170 (72.3)

1

1

 

Weight for height

 Normal

6 (37.5)

178 (75.7)

1

1

 

 Moderate wasting

4 (25.0)

52 (22.1)

2.07 (0.58, 7.35)

1.82(0.53, 6.16)

0.336

 Sever wasting

6 (37.5)

5 (2.1)

21.39(6.86, 66.72)

5.18(1.25, 21.42)

0.023

Height for age

 Normal

6 (37.5)

171 (72.8)

1

1

0.996

 Moderate stunting

6 (37.5)

56 (23.8)

2.71(0.87, 8.40)

1.01(0.01,241.00)

0.998

 Sever stunting

4 (25.0)

8 (3.4)

12.24(3.44, 43.59)

0.70(0.01,1476.91)

0.928

Weight for age

 Normal

6 (37.5)

165 (70.2)

1

1

 

 Under weight

6 (37.5)

59 (25.1)

2.45 (0.79, 7.59)

2.33(0.54, 6.41)

0.431

 Sever under weight

4 (25.0)

11 (4.7)

8.89 (2.49, 31.66)

2.66(0.65, 13.45)

0.311

ART adherence

 Good

8 (50.0)

209 (88.9)

1

1

 

 Fair

2 (12.5)

17 (7.2)

2.72 (0.58, 12.83)

1.27(0.65, 8.22)

0.847

 Poor

6 (37.5)

9 (3.8)

10.89 (3.76, 1.54)

1.49(0.83, 7.54)

0.733

The regimen changed

 No

11 (68.8)

225 (95.7)

6.26 (2.17, 18.07)

5.62(2.34, 82)

0.972

 Yes

5 (31.3)

10 (4.3)

1

1

 
  1. Values in bold font are used to highlight factors with statistically significant impact on survival