Variable | Frequency (n = 161) | Percentage (%) |
---|---|---|
The pharmacokinetics and pharmacodynamics of a medication maybe affected by an individual’s genetic makeup | 149 | 92.5 |
Pharmacogenomics testing can be used to predict medication safety and efficacy | 150 | 93.2 |
Genetic determinants of drugs response may change over a person’s lifetime | 14 | 8.7 |
Genetic variants account for most variability in drug disposition and effects | 118 | 73.3 |
Pharmacogenomics test result can be used to change drug therapy | 153 | 95.0 |
Pharmacogenomics test result can be used for dose adjustment | 144 | 89.4 |
Pharmacogenomics test results can be used as an indication for discontinuation of a drug | 146 | 90.7 |
Indication(s) for pharmacogenomics testing | ||
 Therapeutic failure | 74 | 46.0 |
 To prevent adverse reaction | 112 | 69.6 |
 To guide initiation of therapy | 137 | 85.1 |
 Others |  |  |
Medications that require pharmacogenomics testing | ||
 Paroxetine | 98 | 60.9 |
 Simvastatin | 84 | 52.2 |
 Cefuroxime* | 77 | 47.8 |
 Pantoprazole | 34 | 21.1 |
 Clopidogrel | 48 | 29.8 |
 Ibuprofen* | 137 | 85.1 |
 Warfarin | 86 | 53.4 |