Treatment of Clostridium difficile infection in community teaching hospital: a retrospective study

Table 6 Adherent treatment and overall outcomes

Outcomes	Incidence (%)	Inappropriate treatment (%)	Appropriate treatment (%)	OR	95% CI	P-value
CDI resolution [1] (60 cases)	35/60 (58)	11/35 (31)	24/35 (69)	6.91	2.16–22.10	0.001
30-Day all-cause mortality (60 cases)	14/60 (23)	12/14 (86)	2/14 (14)	9.33	1.87–46.69	0.007
30-Day readmission (37 cases)	8/37 (22)	3/8 (37)	5/8 (63)	0.88	0.18–4.24	0.874
8-Week recurrence (39 cases)	7/39 (18)	3/7 (43)	4/7 (57)	0.97	0.19–4.93	0.971

Incidence of outcomes based on whether inappropriate or appropriate treatment was provided. Patients who received appropriate treatment had statistically more (p = 0.001) cases of CDI resolved (OR = 6.91) ,whereas those who received inappropriate treatment had statistically more (p = 0.007) cases of 30-day all-cause mortality (OR = 9.33). Patients who received appropriate treatment also had a greater percentage of 30-day admission (OR = 0.88) and 8-week recurrence (OR = 0.97); however, its occurrence was not statistically different from the inappropriate treatment arm (p = 0.874, 0.971

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