Repurposing existing drugs for new uses: a cohort study of the frequency of FDA-granted new indication exclusivities since 1997

Table 2 Real and counterfactual number of new indications additions

Time to generic*	Probability of having a new indication		Number of new indications
Time to generic*	Real (%)	Counterfactual (%)	Real	Counterfactual
G_0,5 = 1	1.07	1.29	34	41
G_5,10 = 1	1.64	1.64	45	45
G₁₀₊ = 1	1.80	1.80	34	34
G_neg = 1	0.08	0.37	3	14
Total			116	134

\({G}_{neg}\) indicates observations following generic entry; \({G}_{\mathrm{0,5}}\) observations when generic entry is within 5 years, \({G}_{\mathrm{5,10}}\) observations when generic entry is within 5 to 10 years from 5 to 10 years; \({G}_{10+}\) observations when generic entry is more than 10 years away

ISSN: 2052-3211