Table 4 Appropriateness of antibiotic prescriptions in pre-ASP and post-ASP phases
Parameters of appropriateness of antibiotic use | Pre-ASP intervention (n = 123) (%) | Post-ASP intervention (n = 125) (%) | p value |
|---|---|---|---|
Selection of right antibiotics to target pathogens | 52 (42) | 94 (75) | < 0.01 |
Use of most optimum doses | 30 (24) | 109 (87) | < 0.01 |
Blood levels concentration monitoring | 15 (12) | 100 (80) | < 0.01 |
Drug-interactions | 32 (26) | 15 (12) | < 0.01 |
De-escalation/discontinuation of antibiotics based on definitive diagnosis after 48-h | 25 (20) | 120 (96) | < 0.01 |