Parameters of appropriateness of antibiotic use
|
Pre-ASP intervention (n = 123) (%)
|
Post-ASP intervention (n = 125) (%)
|
p value
|
---|
Selection of right antibiotics to target pathogens
|
52 (42)
|
94 (75)
|
< 0.01
|
Use of most optimum doses
|
30 (24)
|
109 (87)
|
< 0.01
|
Blood levels concentration monitoring
|
15 (12)
|
100 (80)
|
< 0.01
|
Drug-interactions
|
32 (26)
|
15 (12)
|
< 0.01
|
De-escalation/discontinuation of antibiotics based on definitive diagnosis after 48-h
|
25 (20)
|
120 (96)
|
< 0.01
|
- Single patient might appear in no, one or more than one parameter