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Table 1 Combined comparator list of adult and child cardiovascular medicines extracted from 2021 WHO model list of essential medicines

From: A quantitative comparison of essential cardiovascular medicines from countries in the Southern African Development Community to the WHO model essential medicines list

Medication

Dosage form

Comments

Adults

Antianginal medicines

 Bisoprolol

Tablet

Alta: metoprolol; carvedilol

 Glyceryl trinitrate

Tablet/SLb

 

 Isosorbide dinitrate

Tablet/SL

Class effectc

 Verapamil

Tablet

Hydrochloride

Antiarrhythmic medicines

 Bisoprolol

Tablet

Alt: metoprolol; carvedilol

 Digoxin

Tablet/ injection

 

 Epinephrine

Injection

10 ml ampoule; HCL or acid tartrate

 Lidocaine

Injection

5 ml ampoule; HCL

 Verapamil

Tablet/injection

HCLd

 Amiodarone

Tab/injection

3 ml ampoule; HCL (comp)

Antihypertensive medicines

 Amlodipine

Tablet

Maleate, mesylate, besylate; class effect

 Bisoprolol

Tablet

Alt: atenolol; metoprolol; carvedilol

 Enalapril

Tablet

Hydrogen maleate; class effect

Hydralazine

Tablet

HCL; pregnancy-induced hypertension

 Hydrochlorothiazide

Tablet

Alt: chlorothiazide; chlorthalidone; indapamide

 Lisinopril + amlodipine

Tablet

Single pill combination therapy; class effect

 Lisinopril + hydrochlorothiazide (HCT)

Tablet

Single pill combination therapy; class effect

 Losartan

Tablet

Class effect

 Methyldopa

Tablet

Pregnancy-induced hypertension

 Telmisartan + amlodipine

Tablet

Single pill combination therapy; class effect

 Telmisartan + HCT

Tablet

Single pill combination therapy; class effect

 Sodium nitroprusside

Powder for infusion

Complementary

Heart failure medicines

  

 Bisoprolol

Tablet

Alt: metoprolol; carvedilol

 Digoxin

Tablet

 

 Enalapril

Tablet

Hydrogen maleate; class effect

 Furosemide

Tablet/injection

Class effect

 Hydrochlorothiazide

Tablet

 

 Losartan

Tablet

Class effect

 Spironolactone

Tablet

 

 Dopamine

Injection

5 ml vial; HCL; complementary listing

 Antithrombotic medicines

Anti-platelet medicines

 Acetylsalicylic acid

Tablet

 

 Clopidogrel

Tablet

 

Thrombolytic medicines

 Alteplase

Powder for inj

Vial; complementary listing

 Streptokinase

Powder for inj

Vial; complementary listing

Lipid lowering agents

 Simvastatin

Tablets

Use in high-risk patients; class effect

Children

Antihypertensive medication

 Enalapril

Tablet

Hydrogen maleate, class effect

 Enalapril

Suspension

Class effect

Heart failure medicines

 Digoxin

Injection

2 ml ampoule

 Digoxin

Oral Liquid

 

 Digoxin

Tablet

 

 Furosemide

Injection

2 ml ampoule; class effect

 Furosemide

Oral liquid

 

 Furosemide

Tablet

 

 Dopamine

Injection

5 ml vial; HCL; complementary listing

  1. aAlt: recommended alternatives only
  2. bSL: sublingual
  3. cClass effect: recommends any medicine from the same class as that of the listed medicine
  4. dHCL: hydrochloride