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Table 3 Summary of the pharmacists’ impact on patients’ economic, clinical and humanistic outcomes

From: Impact of pharmacist services on economic, clinical, and humanistic outcome (ECHO) of South Asian patients: a systematic review

Authors

Economic

Therapeutic

Safety

Humanistic

IG vs. CG

BI vs. AI

IG vs. CG

BI vs. AI

IG vs. CG

BI vs. AI

IG vs. CG

BI vs. AI

Saeed et al. 2021

–

–

–

–

–

–

QoL++

–

Marasini et al. 2020

–

–

–

 

–

 

Adherence++

QoL*

Adherence#

QoL#

Chatha et al. 2020

–

 

CD4 cell count+

CD4 cell count+

–

 

Adherence+

Medication belief#

Adherence#

Ali et al. 2019

–

–

SVR 12++

ETR*

–

ADE#

DDI#

–

Adherence++

QoL*

QoL++

Javaid et al. 2019

–

–

HbA1C++

eABG+

SBP++

DBP++

Cholesterol++

TG++

HDL*

LDL-C++

VLDL-C++

Serum creatinine++

eGFR++

HbA1C++

eABG++

SBP++

DBP++

Cholesterol++

TG++

HDL*

LDL-C++

VLDL-C++

Serum creatinine++

eGFR++

–

–

–

–

Yadav et al. 2019

–

–

Level of asthma control++

Level of asthma control++

–

–

QoL++

QoL#

Knowledge of MDI use++

Gorutla et al. 2019

–

 

SBP+

DBP+

SBP#

DBP#

–

–

Knowledge++

Attitude++

Practice++

Knowledge#

Attitude#

Practice#

Saleem et al. 2015

–

–

SBP++

DBP++

SBP++

DBP++

–

–

Knowledge++

Adherence++

QoL—

QoL–

Amer et al. 2018

–

–

SBP++

DBP++

SBP++

DBP++

–

–

Knowledge++

Adherence++

QoL++

Knowledge++

Adherence++

QoL++

Abdulsalim et al. 2018

–

 

–

 

–

 

Adherence++

Adherence#

Cooray et al. 2018

–

–

HbA1c#

SBP#

DBP#

TC#

HDL#

TG#

LDL*

BMI*

HbA1c++

TC++

LDL++

SBP*

DBP*

BMI++

–

–

–

–

Upadhyay et al. 2016

DHCs++

DHCs++

–

–

–

–

–

–

Upadhyay et al. 2015

–

–

–

–

–

–

Satisfaction score++

Satisfaction score++

Wal et al. 2013

–

 

SBP#

DBP#

SBP++

DBP++

–

–

QoL#

QoL++

Ramanath et al. 2012

–

–

BP*

BP#

–

–

Adherence++

QOL++

Adherence#

QOL#

Malathy et al. 2011

–

–

PPBG#

TGL#

TC#

HDL#

LDL#

VLDL#

PPBG++

TGL++

TC*

HDL+ 

LDL*

VLDL*

–

–

Knowledge#

Attitude#

Practice*

Knowledge++

Attitude++

Practice*

Sriram et al. 2011

–

–

FBG#

HbA1c#

FBG++

HbA1c++

–

–

QoL#

Treatment satisfaction#

BMI#

QoL++

Treatment satisfaction++

BMI+

Adepu et al. 2010

–

 

SBP#

DBP#

CBG#

SBP+

DBP+

CBG++

–

 

KAP#

Adherence#

KAP++

Adherence#

Adepu et al. 2007

–

–

BG#

BG#

–

–

QoL#

KAP#

QoL#

KAP#

Ponnusankar et al. 2004

–

 

–

 

–

 

Medication

Compliance#

Medication knowledge#

Medication knowledge++

  1. IG vs. CG intervention group versus control group, BI vs. AI before intervention versus after intervention, *no significant (p > 0.05) difference but similar outcome between intervention and control group, +significant (p < 0.05) result in favour of intervention group, ++significant (p < 0.01) result in favour of intervention group, #positive effect in favour of intervention group but no statistical test performed, –significant (p < 0.05) effect in favour of control group; —significant (p < 0.01) effect in favour of control group; SVR 12 = sustained virological response at 12 weeks, FBS fasting blood sugar, ADE adverse drug event, CBC complete blood count, RFT renal function test, ETR end-of-response, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, LDL-C low density lipoprotein-cholesterol, VLDL-C very low density lipoprotein-cholesterol, TGL triglyceride, HDL high density lipoprotein, BG blood glucose; DHCs direct healthcare costs, QoL quality of life, KAP knowledge, attitude and practice