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Table 5 Analysis of the outcomes at the study endpoint

From: Role of clinical pharmacists in epilepsy management at a general hospital in Vietnam: a before-and-after study

 

Before interventions

After interventions

p-value

Monotherapy (n = 99)

Polytherapy (n = 42)

Total (N = 141)

Monotherapy (n = 79)

Polytherapy (n = 37)

Total (N = 116)

Treatment effectiveness, n (%)

 Good control

61

18

79 (56.0)

66

28

94 (81.0)

 < 0.001*

 Poor control

38

24

62 (44.0)

13

9

22 (19.0)

 

Drug serum concentration, n (%)

 Within therapeutic range

57

16

73 (51.8)

53

24

77 (66.4)

0.018*

 Outside therapeutic range

42

26

68 (48.2)

26

13

39 (33.6)

 

Worst and best case analysis

  

Total (N = 141)

  

Total (N = 141)

 

Worst case

 Treatment effectiveness, n (%)

  Good control

–

–

79 (56.0)

–

–

94 (66.7)

0.067*

  Poor control

–

–

62 (44.0)

–

–

47 (33.3)

 Drug serum concentration, n (%)

  Within therapeutic range

–

–

73 (51.8)

–

–

77 (56.0)

0.633*

  Outside therapeutic range

–

–

68 (48.2)

–

–

64 (44.0)

Best case

 Treatment effectiveness, n (%)

  Good control

–

–

79 (56.0)

–

–

119 (84.4)

< 0.001*

  Poor control

–

–

62 (44.0)

–

–

22 (15.6)

 Drug serum concentration, n (%)

  Within therapeutic range

–

–

73 (51.8)

–

–

102 (73.8)

< 0.001*

  Outside therapeutic range

–

–

68 (48.2)

–

–

39 (26.2)

  1. *Chi-square test, conducted between the total before and after the interventions
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Journal of Pharmaceutical Policy and Practice

ISSN: 2052-3211

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