Table 2 Comparison of study outcomes in pre and post-implementation phases
Study outcome | Pre-pharmacist directed-TDM phase | Post-pharmacist directed-TDM phase | Mean difference (95% CI) | p value |
|---|---|---|---|---|
Optimum prescribed initial VCM doses | 45.0% (45/100) | 96% (96/100) | 0.22 (0.14–0.36) | < 0.0001 |
Optimum VCM-dosage adjustments | 50.6% (83/164) | 88.8% (95/107) | 0.29 (0.15–0.42) | < 0.05 |
Optimum VCM-sampling time | 37.6% (82/218) | 58.9% (168/285) | 0.15 (− 0.05–0.26) | 0.079 |