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Table 3 Demographics and clinical background of participants (N = 1080)

From: Incidence of adverse reaction of drugs used in COVID-19 management: a retrospective, observational study

Variable

Patients with ADR (n = 217)

Patients without ADR (n = 863)

P value

Age (mean ± SD in years)

47.96 ± 16.50

40.07 ± 16.51

< 0.001†

Sex

     Male

137 (63.1%)

593 (68.7%)

0.116‡

     Female

80 (36.9%)

270 (31.3%)

 

History of drug allergy

     Yes

5 (2.3%)

26 (3.0%)

0.576‡

     No

212 (97.7%)

837 (97.0%)

 

Presence of comorbidity

     Yes

117 (53.9%)

294 (34.1%)

< 0.001‡

     No

100 (46.1%)

569 (65.9%)

 

COVID-19 category

     Patient under investigation

9 (4.1%)

80 (9.3%)

 

     Stage 1

1 (0.5%)

35 (4.1%)

 

     Stage 2

27 (12.4%)

357 (41.4%)

 

     Stage 3

85 (39.1%)

311 (36.0%)

 

     Stage 4

79 (36.4%)

58 (6.7%)

 

     Stage 5

16 (7.4%)

22 (2.5%)

 

Number of COVID-19 drug(s)

     1

51 (23.5%)

704 (81.6%)

 

     2

96 (44.2%)

115 (13.3%)

 

     3

46 (21.2%)

30 (3.5%)

 

     4 and 5

24 (11.1%)

14 (1.6%)

 
  1. Data are n (%) or mean (± SD)
  2. †Analysed with Mann–Whitney U test
  3. ‡Analysed with Chi-square (X2) test