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Table 2 Characteristics of the included studies

From: Drug-related problems and associated factors in Ethiopia: a systematic review and meta-analysis

Author Year Design Population Study area Department of the hospital at which study performed Medical condition Sample size Number with Event (DRPs) Total number of event (DRPs) Sub-types of drug therapy problems Sub-types of DRPs
Unnecessary drug therapy Need additional drug therapy Ineffective drug Low dose High dose Adverse drug reaction Non-compliance
Mohammednur et al [45] 2014 Cross-sectional Adult Adama Referal Hospital Ambulatory care Hypertension 192 155 452 10    90 81 179 86
Gebre et al [34] 2017 Cross-sectional Adult Tikur Anbessa Specialized Hospital Ambulatory care Diabetes 418 177 207 20 52 54 58 5 18  
Gobezie et al [46] 2014 Cross-sectional Adult Ambo General Hospital Ambulatory care Hypertension 151 118 200 37 24 19 24   15 81
Gobezie et al [24] 2013 Prospective general cohort study Adult Felege Hiwot Referal Hospital Ambulatory care Heart failure 76 73 104   57 11 6 10 20  
Aster et al [26] 2019 Prospective general cohort study Adult Jimma University Medical Centre Medical ward Chronic kidney disease 103 81 200 9 62 20 36 29 4 40
Yaschilal et al [43] 2014 Prospective general cohort study Adult Dessie Referal Hospital Medical ward Mixed 147 111 159 48 57 3 21 6 15 9
Abadir et al [47] 2015 Cross-sectional Adult Dilchora Referal Hospital Ambulatory care Hypertension 271 193 318 5 182 21     124
Gashaw et al [54] 2016 Cross-sectional Adult Gondar University Referal Hospital Medical ward Mixed 256 169 174 7 42   36 32 8 25
Yirga et al [27] 2015 Prospective observational study Adult Jimma University Medical Centre Ambulatory care Heart failure 340 284 883 34 241 243 245 14 26 80
Tamene et al [28] 2014 Prospective observational study Adult Jimma University Medical Centre Medical ward Mixed 152 115 221 45 48 14 48 23 14 29
Bereket et al [29] 2014 Cross-sectional Adult Jimma University Medical Centre Medical ward Mixed 257 189 316 47 103 42 44 49   31
Mohammed et al [30] 2016 Cross-sectional Adult Jimma University Medical Centre Ambulatory care Diabetes and Hypertension 300 70 494 51 145 138 78 9 13 60
Mequanent et al [55] 2014 Cross-sectional Paediatrics Zewditu Referal Hospital Paediatrics ward Mixed 285 90 106 8 3   35 36 24  
Asgedom et al [48] 2016 Cross-sectional Adult Ayder Referal Hospital Ambulatory care Hypertension 241 134 357 40 61 44 60 3 6 143
Kaleab et al [49] 2015 Cross-sectional Adult G/Tsadik Shawo General Hospital Ambulatory care Heart failure 132 86 163 10 54 17 4 11 21 46
Eskinder et al [35] 2013 Cross-sectional Adult Tikur Anbessa Specialized Hospital Ambulatory care Cancer 367 274 474 62 30 65 69 78 170  
Hailu et al [50] 2015 Cross-sectional Adult Wolaita Referal Hospital Ambulatory care Diabetes 243 202 378 16 137 8 65 14 11 127
Malede et al [36] 2018 Prospective observational study Paediatrics Tikur Anbessa Specialized Hospital Ambulatory care Cancer 176 107 257 25 70 11 60 41 14 36
Beshir et al [37] 2017 Cross-sectional Adult Tikur Anbessa Specialized Hospital Ambulatory care Epilepsy 191 134 352 3 18 98 39 33 161  
Elham et al [25] 2017 Cross-sectional Adult Tikur Anbessa Specialized Hospital Ambulatory care Heart failure 423 277 572 31 69 100 129 82 161  
Mohammed et al [38] 2014 Cross-sectional Adult Tikur Anbessa Specialized Hospital Medical ward Mixed 225 117 152 7 17 4 11 34 59  
Tadele et al [53] 2015 Prospective observational study Adult Mizan, Bonga & Teppi General Hospital Medical ward Mixed 348 233 390 58 91 45 65 46 22 63
Ayele et al [41] 2017 Cross-sectional Adult Madda-Walabu University Goba Referal Hospital Ambulatory care Diabetes 216 190 446 16 224 28 55 3 23 97
Tamene et al [42] 2017 Cross-sectional Adult Hiwot Fana Specialized University Hospital Ambulatory care Heart failure 216 131 131 16 76 9 14    16
Haymen et al [40] 2018 Cross-sectional Adult Hiwot Fana Specialized University Hospital Ambulatory care Diabetes 148 127 127 25   25 46    31
Berhane et al [31] 2017 Prospective observational study Adult Jimma University Medical Centre Medical and Surgical ward Mixed 200 161 449 81 69 181    92 26
Gobezie et al [50] 2013 General cohort study Adult Jimma University Medical Centre & Felege Hiwot Referal Hospital Ambulatory care Heart failure 97 86 179 7 106 12 5 27 22  
Yohannes et al [41] 2017 Cross-sectional Adult Hiwot Fana Specialized University Hospital Ambulatory care Diabetes and hypertension 203 179 364 39 77     69 179
Bereket et al [32] 2013 Cross-sectional Adult Jimma University Medical Centre Medical ward Mixed 257 140 316 47 103 42 44 49   31
Gizachew et al [44] 2018 Prospective observational study Paediatrics Dessie Referal Hospital Paediatrics ward Mixed 81 71 119 20 30 3 22 10 10 24
Gubae et al [39] 2017 Cross-sectional Adult Tikur Anbessa Specialized Hospital Ambulatory care Schizophrenias 117 62         
Gosaye et al [33] 2017 Cross-sectional Adult Jimma University Medical Centre Surgical ward Mixed 300 228 418 66 52 21 124 81 26 48