Table 1 a Baseline characteristics of study participants/pregnant women (n = 344); b Baseline characteristics of study variables related to prescribed antimicrobials (n = 688)
Variables | Group | Frequency (n) | Percentage (%) |
|---|---|---|---|
(a) | |||
Age | 15–24 | 77 | 22.4 |
25–34 | 191 | 55.5 | |
35–44 | 73 | 21.3 | |
≥ 45 | 3 | 0.9 | |
Drug resistance (n = 324) | No | 272 | 84.0 |
Yes | 52 | 16.0 | |
B-lactam | 20 | 38.5 | |
MDR | 17 | 32.7 | |
Quinolones | 15 | 28.8 | |
Mode of delivery | Vaginal delivery | 245 | 71.2 |
C-section | 99 | 28.7 | |
Mother comorbidities | No | 198 | 56.9 |
Yes | 146 | 42.4 | |
Maternal complications | Abortions | 205 | 29.8 |
Preterm pregnancies | 152 | 22.1 | |
Fetal complications | No | 297 | 86.3 |
Yes | 47 | 13.6 | |
(b) | |||
Antimicrobial use per trimester (n = 685) | First | 148 | 21.6 |
Second | 212 | 30.9 | |
Third | 325 | 47.4 | |
FDA category for safety drug use during pregnancy | Category A | 0 | 0 |
Category B | 457 | 66.4 | |
Category C | 224 | 32.6 | |
Category D | 7 | 1.0 | |
Category X | 0 | 0 | |
Allergy | No | 633 | 92.0 |
Yes | 55 | 8.0 | |
B-lactam | 12 | 21.8 | |
Dopaminergic | 11 | 20.0 | |
Quinolones | 7 | 12.7 | |
NSAIDs | 6 | 10.9 | |
Food allergy | 6 | 10.9 | |
Danozol | 3 | 5.5 | |
Multi drug allergy | 3 | 5.5 | |
Corticosteroids | 2 | 3.6 | |
Tetracycline | 2 | 3.6 | |
Miscellaneous | 2 | 3.6 | |
Sulfa drug | 1 | 1.8 | |
Indication of antibiotic use | Treatment | 681 | 99.0 |
Prophylaxis | 7 | 1.0 | |