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Table 2 Medication appropriateness index (MAI) scores; ITT analysis

From: General practitioner practice-based pharmacist input to medicines optimisation in the UK: pragmatic, multicenter, randomised, controlled trial

Outcome measures Control Intervention p value
n = 60 (48.8%)* n = 63 (51.2%)*
Baseline End Differencea Baseline End Differencea
Number of medications scored (total) 620 601   628 602   
Mean ± SD# 10.3 ± 3.6 10.0 ± 3.9   10.0 ± 3.8 9.6 ± 3.9   
Median [IQR]# 10 [7.3–12.0] 10 [6.3–12.0]   9 [7.0–12.0] 9 [7.0–11.0]   
Summated MAI score per patient, mean ± SD 9.1 ± 7.3 9.1 ± 8.5 0.0 ± 4.0 9.6 ± 7.6 7.2 ± 8.1 2.4 ± 4.8 0.879b
 < 0.001c
0.001d
Median [IQR] 8 [313] 7 [312] 0 [0–0] 8 [4–13] 5 [0–11] 0 [0–5]
  1. Bold values denote statistical significance at the p < 0.05 level
  2. *Random sample (random.org) of one-third of the total sample in every practice, #Medications per patient
  3. aCalculated as MAI score at baseline – MAI score at end of study
  4. bWilcoxon signed rank test in control group, between baseline and end of study
  5. cWilcoxon signed rank test in intervention group, between baseline and end of study
  6. dMann–Whitney U test between groups at end of study for MAI difference