Skip to main content

Table 1 Patients’ characteristics and clinical indications for antibiotic in pre-ASP and post-ASP phases-ASP

From: An antibiotic stewardship program in a surgical ICU of a resource-limited country: financial impact with improved clinical outcomes

Variable

Pre-ASP intervention (n = 123) (%)

Post-ASP intervention (n = 125) (%)

p value

Demographic characteristics

 Age (years)*

51 (11.2)

53 (9.5)

0.87

 Gender (male)

88 (72)

93 (74)

0.68

Comorbidities**

 Cardiovascular illnesses

21 (17)

23 (18)

0.86

 Chronic hepatobiliary illnesses

12 (10)

13 (10)

 

 Chronic renal illnesses

8 (7)

7 (6)

 

 Diabetes mellitus

30 (24)

32 (26)

 

 Malignancies

0

0

 

 Chronic neurological/neuropsychiatric illnesses

3 (2)

4 (3)

 

 Chronic respiratory illnesses

5 (4)

4 (3)

 

 ≥ 2 chronic medical illnesses

8 (7)

7 (6)

 

 No comorbid condition

36 (29)

35 (28)

 

Clinical indications for antibiotics in SICU

 Prophylaxis

58 (47)

55 (44)

0.78

 Empirical

43 (35)

45 (36)

 

 Therapeutic

22 (18)

25 (20)

 

Surgeries specialty involved

 General surgery

53 (43)

56 (45)

0.75

 Neurosurgery

42 (34)

40 (32)

 

 Orthopedic

15 (12)

18 (14)

 

 Obs/gyn

7 (6)

6 (5)

 

 ENT

4 (3)

3 (2)

 

 Vascular

2 (2)

2 (2)

 
  1. SICU surgical intensive care unit, ASP antibiotic stewardship program,Obs/gyn obstetrics and gynecological, ENT ears, nose and throat, ns not significant
  2. *Mean (SD)
  3. **Comorbidities were coded from the World Health Organization, International Classification of Diseases, 10th revision, Clinical Modification (ICD-10) [23]