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Table 8 Change in HbA1c with DPP-4i use, N = 47 (patients without insulin)

From: Dipeptidyl Peptidase-4 inhibitors use in type II diabetic patients in a tertiary hospital

Type of DPP-4i

n (%)

Pre DPP-4i use

Post DPP-4i use

Mean difference (95% CI)

P value£

P value¥

Vildagliptin

20 (42.6)

7.7 ± 0.9

6.7 ± 0.8

1.03 (0.37, 1.68)

0.004*

0.104¢

Sitagliptin

13 (27.7)

8.8 ± 2.1

7.1 ± 1.4

1.69 (0.25, 3.13)

0.025*

Saxagliptin

13 (27.7)

7.8 ± 1.3

7.4 ± 1.1

0.32(−0.06, 0.71)

0.094

Linagliptin

1 (2.1)

    
  1. £Paired T-test conducted to compare pre and post DPP-4i HbA1c
  2. ¥ANOVA conducted to compare the HbA1c difference between the groups
  3. Values reported as mean ± SD
  4. *p value is significant at< 0.05
  5. Linagliptin omitted from analysis as n = 1