Type of PIMs according to STOPP criteria | Control group N (%) | Intervention group N (%) |
---|---|---|
Drug Indication Criteria | ||
āāAny duplicate drug class prescriptionā | 2 (0.8) | 0 |
Coagulation System | ||
āāAspirin plus clopidogrel as secondary stroke prevention, unless the patient has a coronary stent(s) inserted in the previous 12āmonths or concurrent acute coronary syndrome or has a high grade symptomatic carotid arterial stenosisā | 3 (1.3) | 0 |
āāAspirin in combination with vitamin K antagonist, direct thrombin inhibitor or factor Xa inhibitors in patients with chronic atrial fibrillationā | 1 (0.4) | 0 |
āāTiclopidine in any circumstancesā | 5 (2.1) | 7 (2.9) |
Central Nervous System and Psychotropic Drugs | ||
ā āFirst-generation antihistaminesā | 1 (0.4) | 1 (0.4) |
Renal System | ||
ā āNSAIDās if eGFR <ā50āml/min/1.73m2ā | 1 (0.4) | 1 (0.4) |
ā āMetformin if eGFR <ā30āml/min/1.73m2ā | 6 (2.5) | 4 (1.7) |
Gastrointestinal System | ||
ā āDrugs likely to cause constipation in patients with chronic constipation where non-constipating alternatives are availableā | 1 (0.4) | 0 |
ā āProton pump inhibitor for uncomplicated peptic ulcer disease or erosive peptic oesophagitis at full therapeutic dosage for >ā8āweeksā | 14 (5.8) | 13 (5.4) |
Respiratory System | ||
ā āAnti-muscarinic bronchodilators with a history of narrow-angle glaucoma or bladder outflowā | 2 (0.8) | 0 |
Musculoskeletal System | ||
ā āLong-term NSAID or colchicine (>ā3āmonths) for chronic treatment of gout where there is no contraindication to a xanthine-oxidase inhibitorā | 2 (0.8) | 1 (0.4) |
Endocrine System | ||
ā āSulphonylureas with a long duration of action with type 2 diabetes mellitusā | 1 (0.4) | 0 |
ā āBeta-blockers in diabetes mellitus with frequent hypoglycaemic episodesā | 10 (4.2) | 4 (1.7) |
Drugs that predictably increase the risk of falls in older people | ||
ā āVasodilator drugs with persistent postural hypotensionā | 23 (9.6) | 24 (10%) |
Analgesic Drugs | ||
ā āUse of regular opioids without concomitant laxativeā | 0 | 4 (1.7) |