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Table 1 Reported global annual product sales by calendar year for selected medicines according to company annual reports (2004–2017) (in million USD)a

From: Supplementary protection certificates and their impact on access to medicines in Europe: case studies of sofosbuvir, trastuzumab and imatinib

Year

Sovaldi® (sofosbuvir) Gilead [47]

Herceptin® (trastuzumab) Roche & Genentech [48]

Gleevec/Glivec® (imatinib) Novartis [49]

2004

N/A

1162

1634

2005

N/A

1717

2170

2006

N/A

3142

2554

2007

N/A

4027

3050

2008

N/A

4736

3944

2009

N/A

4845

3944

2010

N/A

5212

4265

2011

N/A

5936

4659

2012

N/A

6301

4675

2013

139

6565

4693

2014

10,283

6840

1237

2015

5276

6800

1219

2016

4001

6918

3323

2017

964

7154

1943

Total

20,663

34,277

43,310

  1. aAmounts rounded to millions. Trastuzumab sales have been converted from CHF to USD using historical exchange rates