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Table 2 Number of patients with a NVP-to-PI substitution

From: Assessment of the nevirapine safety signal using data from the national antiretroviral dispensing database: a retrospective study

Time after starting ART (number of weeks) Number of NVP to PI substitutions Total
2008 2009 2010 2011
2 3 7 2 12 24
4 1 6 23 12 42
6 6 8 24 32 70
8 4 6 11 26 47
10 1 4 7 12 24
12 2 4 9 10 25
14 3 5 6 3 17
16 3 2 3 4 12
18 0 1 2 4 7
20 1 4 3 4 12
22 1 1 1 2 5
24 0 0 2 3 5
Total 25 48 93 124 290
  1. Throughout the period that was assessed, the majority of NVP-to-PI substitutions took place within the first12 weeks of ART. Higher numbers of substitutions are observed in 2010 and even higher in 2011 than the two previous years