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Table 1 Changes in the utilization (DDDs per 100 hypertensive patients per year) of antihypertensive medications among the Palestine refugee hypertensive patient population in Jordan between 2008 (pre-STG) and 2012 (post-STG)

From: Trends in the utilization of antihypertensive medications among Palestine refugees in Jordan, 2008-2012

ATC codes Therapeutic class Antihypertensive utilization, % of total Change in utilization Percent change in utilization
2008 2012 2008-2012 2008-2012
  Total** 280.5 (100%) 275.3(100%) −5.23 −1.86%
C02AB01 Alpha-adrenergic agonists 2.22 (0.8%) 2.55 (0.9%) +0.33 +14.86%
C09AA02 ACE inhibitors** 178.1 (63.5%) 132.5 (48.1%) −45.67 −25.64%
C09CA01 Angiotensin II receptor antagonists** 0 (0%) 7.7 (2.8%) +7.71 -
C07AA05, C07AB03 Beta blockers 53.9 (19.2%) 55.4 (20.1%) +1.43 +2.65%
C08CA05, C08DB01, C08CA01 Calcium channel blockers 23.8 (8.5%) 26.97 (9.8%) +3.2 +13.46%
C03AA03,C03AX01, C03CA01,C03DB01 Diuretics** 22.4 (8.0%) 50.2 (18.2%) +27.77 +123.9% (only more than 100% is significant)
  1. DDD = defined daily dose, ACE = Angiotensin-converting enzyme; Standard Treatment Guidelines (STG) for hypertension management implemented in 2009 at UNRWA primary health clinics (PHCs).
  2. **The binomial proportion 95% confidence interval excludes the null value of zero difference (P-value <0.05).