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Table 5 Susceptibility of organisms isolated from CSF

From: Antimicrobial sensitivity patterns of cerebrospinal fluid (CSF) isolates in Namibia: implications for empirical antibiotic treatment of meningitis

Organism Antimicrobial Total, N S S, % R R, % I I, %
Streptococcus 206 isolates Ciprofloxacin 34 34 100 0 0   0
  Ceftriaxone 89 87 97.8 2 2.2 0 0
  Ofloxacin 40 39 97.5 1 2.5 0 0
  Cefuroxime 28 27 96.4 1 3.6 0 0
  Chloramphenicol 171 160 93.6 9 5.3 2 1.2
  Vancomycin 110 102 92.7 6 5.5 2 1.8
  Erythromycin 186 162 87.1 23 12.4 1 0.5
  Clindamycin 140 120 85.7 19 13.6 1 0.7
  Tetracycline 180 146 81.1 25 13.9 9 5
  Gentamicin 5 4 80 1 20 0 0
  Amoxicillin 24 18 75 6 25 0 0
  Penicillin 169 109 64.5 58 34.3 2 1.2
  Oxacillin 153 79 51.6 69 45.1 5 3.3
  Sulfamethoxazole/trimethoprim 175 48 27.4 125 71.4 2 1.1
Neisseria meningitidis 107 isolates Chloramphenicol 102 97 95.1 3 2.9 2 2
  Ceftriaxone 105 97 92.4 5 4.8 3 2.9
  Penicillin 105 86 81.9 16 15.2 3 2.9
  Erythromycin 14 10 71.4 4 28.6 0 0
  Tetracycline 24 17 70.8 3 12.5 4 16.7
  Sulfamethoxazole/trimethoprim 102 22 21.6 79 77.5 1 1
Haemophilus 59 isolates Amoxicillin 53 32 60.4 18 34 3 5.7
  Amoxicillin/Clavulanic Acid 18 14 77.8 4 22.2   0
  Ceftriaxone 52 46 88.5 5 9.6 1 1.9
  Cefuroxime 20 14 70 5 25 1 5
  Chloramphenicol 55 48 87.3 6 10.9 1 1.8
  Ciprofloxacin 11 11 100 0 0   0
  Ofloxacin 23 22 95.7 0 0 1 4.3
  Penicillin 6 6 100   0   0
  Tetracycline 27 21 77.8 4 14.8 2 7.4
  Sulfamethoxazole/trimethoprim 37 10 27 25 67.6 2 5.4
Staphylococcus 36 isolates Amikacin 7 7 0 0 0 0 0
  Vancomycin 22 20 90.9 0 0 2 9.1
  Fusidic acid 34 29 85.3 1 2.9 4 11.8
  Ciprofloxacin 21 17 81 4 19   0
  Cephalothin 8 6 75 2 25 0 0
  Clindamycin 27 19 70.4 6 22.2 2 7.4
  Tetracycline 27 19 70.4 8 29.6   0
  Erythromycin 31 21 67.7 10 32.3 0 0
  Oxacillin 9 6 66.7 3 33.3 0 0
  Cloxacillin 29 19 65.5 10 34.5   0
  Cefuroxime 5 3 60 2 40 0 0
  Gentamicin 17 7 41.2 9 52.9 1 5.9
  Penicillin 34 8 23.5 25 73.5 1 2.9
  Amoxicillin 14 3 21.4 11 78.6 0 0
  Sulfamethoxazole/trimethoprim 29 0 0 18 62.1 11 37.9
Escherichia coli 22 isolates Ceftriaxone 17 17 100   0   0
  Chloramphenicol 6 6 100   0   0
  Ciprofloxacin 13 12 92.3 1 7.7   0
  Cefuroxime 19 15 78.9 2 10.5 2 10.5
  Piperacillin-Tazobactam 4 3 75 1 25   0
  Cephalothin 10 7 70 1 10 2 20
  Gentamicin 17 11 64.71 3 17.65 3 17.65
  Tetracycline 5 3 60 2 40   0
  Amoxicillin/Clavulanic Acid 7 4 57.14 3 42.86   0.0
  Erythromycin 4 2 50 2 50   0
  Penicillin 4 2 50 2 50   0
  Sulfamethoxazole/trimethoprim 21 3 14.29 18 85.71   0
  Amoxicillin 22 3 13.6 19 86.4   0
Enterococcus species 9 isolates Penicillin 8 7 87.5 1 12.5 0 0
  Vancomycin 9 7 77.8 1 11.1 1 11.1
  Amoxicillin 7 5 71.4 2 28.6 0 0
  Ciprofloxacin 3 2 66.7 1 33.3   0
  Erythromycin 3 1 33.3 2 66.7 0 0
  Clindamycin 8 2 25 6 75 0 0
  Tetracycline 2 0 0 2 100 0 0
  Sulfamethoxazole/trimethoprim 2 0 0 2 100 0 0
Acinetobacter species 8 isolates Imipenem 8 7 87.5 1 12.5   0
  Sulfamethoxazole/trimethoprim 7 6 85.7 1 14.3   0
  Gentamycin 8 6 75 2 25 0 0
  Piperacillin-Tazobactam 8 6 75 1 12.5 1 12.5
  Ceftazidime 6 4 66.7 1 16.7 1 16.7
  Piperacillin 2 1 50 1 50   0
Klebsiella 7 isolates Ciprofloxacin 5 5 100   0   0
  Amikacin 6 5 83.3 1 16.7   0
  Ceftriaxone 7 5 71.4 2 28.6   0
  Gentamicin 6 4 66.7 1 16.7 1 16.7
  Piperacillin-Tazobactam 3 2 66.7 1 33.3   0
  Cefuroxime 6 3 50 2 33.3 1 16.7
  Sulfamethoxazole/trimethoprim 7 3 42.9 4 57.1   0
  Cephalothin 5 1 20 4 80 0 0
  Amoxicillin 7 1 14.3 4 57.1 2 28.6
ESBL’s Klebsiella pneumoniae 7 isolates Amikacin 7 5 71.43 1 14.3 1 14.3
  Ciprofloxacin 7 7 100   0   0
  Imipenem 7 7 100   0   0
  Piperacillin-Tazobactam 7 7 100   0   0
  Ceftazidime 7 2 28.6 5 71.4   0
  Amoxicillin 7   0 7 100   0
  Ceftriaxone 7   0 7 100   0
  Cefuroxime 7   0 7 100   0
  Gentamicin 7   0 7 100   0
  Sulfamethoxazole/trimethoprim 7   0 7 100   0
Pseudomonas species 7 isolates Amikacin 7 7 100   0   0
  Ceftazidime 7 7 100   0   0
  Ciprofloxacin 6 6 100   0   0
  Imipenem 6 6 100   0   0
  Gentamycin 6 5 83.3 1 16.7 0 0
  Piperacillin-Tazobactam 7 4 57.1   0 3 42.9
  Sulfamethoxazole/trimethoprim 7 3 42.9 4 57.1   0
  1. Source: MEDITECH Database 2009–2012. legend: S=sensitive; R=resistant and I=indeterminate.